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The Problem: Excessive Cellular Burden and The Cell Danger Response

The rise in modern lifestyle has matched the rise in cell danger response.

The modern and post-modern eras have come with an increasing rise in poor food, environmental toxins, blue light, WiFi, time spent indoors, pharmaceuticals, vaccines, sedentary lifestyles, stress, and unfortunately several types of diseases and chronic illnesses.

But is there a connection between this modern way of life and the rise of chronic illness?

Let’s consider 6 classes of modern illnesses that share a similar and alarming rise in frequency.

  1. Inflammatory or Immune Response Syndromes (SIRS, CIRS, MCAS, Asthma, Allergies, etc.)
  2. Metabolic Diseases (diabetes, high blood pressure, heart disease, obesity etc.)
  3. Cancers and Leukemias
  4. Mental Health Disorders (depression, anxiety, schizophrenia, PTSD etc.)
  5. Autoimmune Diseases (RA, AS, Lupus, MS, Hashimoto’s, Parkinson’s, etc.)
  6. Gastro-Intestinal Functional Disorders (IBS, microbial overgrowths, Crohn’s, etc.)

Types of common chronic illnesses

The work of Dr. Robert Naviaux found that these diseases all had a unique metabolic signature or biochemical signature.

In fact, it was found that you could identify the presence of disease by observing the biochemistry and metabolites of a person’s blood at an alarming 80%+ rate and higher.

But that’s not the important part.

What’s most astounding is the fact that all of the chronic diseases noted, shared one common piece in their metabolic signature.

And that was the metabolites of the biochemical pathways of cellular stress (coined ‘cell danger response’).

Simply stated, the one thing common among chronic diseases is the fact that the cells of the host are responding to a present threat or stress.

Why would this make one susceptible to disease?

  1. First, there is the obvious damaging impact of stress and toxins.
  2. Second, and especially critical to understanding chronic illness, is the fact that in response to threats to the well-being and survival of the cell – the cell turns off several critical functions of optimal function and health and turns on several new genes (and therefore biochemical pathways) that allow it to begin to address the emergency and threat at hand before returning to optimal and healthy functioning.

Among the critical changes, are changes in the function of the mitochondria. In fact, the mitochondria abandon the life-critical synthesis of ATP / energy in favor of new functions that help signal danger to the cell and surrounding cells.

Throughout the response to threat and stress the cell and mitochondria both take on different forms and functions. These different states that the mitochondria and cell can take on help the cell accomplish 4 critical objectives that allow it to return to proper and optimal function. You will learn more about these 4 objectives in The Bear Protocol. For now, it’s only important to note that specific categories of chronic illness and disease exist when and where the mitochondria and cells of the body take on specific unsustainable forms and functions.

In fact, specific types and groups of illnesses exist when the cells remain in specific functional states.

For example, inflammatory and innate immune diseases (think asthma, allergies, MCAS etc.) occur when the cells are trying to slow and contain a threat or toxin.

Note that the cell is trying. If the cell succeeds it can move on to other functions but if the threat, stress or toxin remains – or if the cell lacks the resources to or is otherwise unable to effectively contain the threat it remains responding to danger rather than returning to its proper form and function.

From Heart Disease and Cancer to Mental Health Disorders and Autoimmune Conditions

The worst diseases of our day – both in volume but also in the negative impact on quality of life, have risen in correlation with the previously mentioned environmental and lifestyle factors. And although it will be some time (or quite some time) before the traditional system acknowledges or implements the implications of this powerful finding – the truth remains that chronic illnesses occur when and where cells are in the process of responding to a burden greater than they are equipped to handle.

Illnesses that remain until the cells of the host can properly escape or address the present threat and burden:

Chronic disorders of the modern and contemporary eras

We will make more sense of this later, but for now, understand that specific types of chronic illness share the fact that they exist when responding to danger.

In The Bear Protocol, you learn each of the 4 phases in the cells and nervous system’s response to danger. And perhaps far more importantly it focuses on the specific methods to support each phase of the stress response so that the mitochondria and cells can return to their proper function.

Please read on to The Bear Protocol to understand the four phases of cell danger response and their correlating chronic illnesses.

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